Heart Failure Patients’ Adherence to Hybrid Comprehensive Telerehabilitation and Its Impact on Prognosis Based on Data from TELEREH-HF Randomized Clinical Trial

(1) Background Adherence to treatment guidelines in heart failure (HF) patients is of major prognostic importance, but thorough implementation routine care remains insufficient. Introducing hybrid comprehensive telerehabilitation (HCTR) consisting telecare, telerehabilitation, and remote monitoring implantable devices might be an option improve adherence recommendation can affect the prognosis. The purpose investigate association HCTR with mortality hospitalization. (2) Methods This analysis formed part TELEREH-HF multi-center, randomized trial that enrolled 850HF (NYHA I-III;LVEF ≤ 40%). Patients were 1:1 9-week (1 week hospital 8 weeks at home) plus usual or only followed-up for 14 26 months. focuses on group. Adherent those who adhered both number training sessions prescribed duration cycle by least 80%; non-adherent adhered<20% their duration. remaining classified as partially adherent. (3) Results There 350 (88.4%) adherent patients, 39 (9.8%) 7 (1.8%) patients. 46 deaths during follow-up. Non-adherence partial was associated higher risk cardiovascular (CV) (hazard ratio (HR) = 2.62, p 0.021); all-cause HF hospitalization (HR 1.71, 0.038); CV 1.89, 0.014). (4) Conclusions high. improved prognosis reduction combined outcome